加拿大实验室生物安全手册和标准的发展历程及其启示
摘要：介绍了加拿大实验室生物安全手册和标准的发展历程，研究了其修订的思路和发展趋势，重点从国家标准的必要性、标准指南的互补性、同一个健康的理念、性能验证的重要性4个方面探讨了我国实验室生物安全标准的发展方向，为我国生物安全相关标准的制修订提供参考。
关键词：实验室生物安全加拿大标准手册发展方向
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参考文献[1] 亚太建设科技信息研究院有限公司，同济大学.生物安全实验室建设与发展报告[M].北京：科学出版社，2021:46-47.
[2] Health Canada.Laboratory biosafety guidelines[M].2nd ed.Ottawa:Minister of Supply and Services,1996:1-10.
[3] Public Health Agency of Canada.Laboratory biosafety guidelines[M].3rd ed.Ottawa:Minister of Public Works and Government Services,2004:1-12.
[4] Public Health Agency of Canada.Canadian biosafety standards and guidelines[M/OL].[2022-04-01].http://canadianbiosafetystandards.collaboration.gc.ca.
[5] Canadian Food Inspection Agency.Containment standards for veterinary facilities[S].Ottawa:Agriculture and Agri-Food Canada,Minister of Supply and Services Canada,1996:1-30.
[6] Canadian Food Inspection Agency.Containment standards for laboratories,animal facilities and post mortem rooms handling prion disease agents[S].Ottawa:Canadian Food Inspection Agency,2005:1-10.
[7] Public Health Agency of Canada.Canadian biosafety standards (2nd ed)[S/OL].[2022-04-01].http://canadianbiosafetystandards.collaboration.gc.ca.
[8] Public Health Agency of Canada.Canadian biosafety handbook[M].2nd ed.Ottawa:Minister of Health and the Minister of Agriculture and Agri-Food,2016:1-60.
[9] U.S.Center for Disease Control and Prevention.Biosafety in microbiological and biomedical laboratories(6th edition)[M/OL].[2022-04-01].https://www.cdc.gov/labs/BMBL.html.
[10] 中国合格评定国家认可中心，国家质量监督检验检疫总局科技司，中国疾病预防控制中心，等.实验室生物安全通用要求：GB 19489—2008[S].北京：中国标准出版社，2008:7-11,23-24.
[11] 中国建筑科学研究院，江苏双楼建设集团有限公司.生物安全实验室建筑技术规范：GB 50346—2011[S].北京：中国建筑工业出版社，2012:5-9,32.
[12] 加拿大公共卫生署.加拿大生物安全标准与指南[M].赵赤鸿，李晶，刘艳，译.北京：科学出版社，2017:Ⅵ.
[13] 曹冠朋，曹国庆，张彦国，等.国内外生物安全实验室标准体系检测要求对比[J].暖通空调，2022,52(2):16-22.
[2] Health Canada.Laboratory biosafety guidelines[M].2nd ed.Ottawa:Minister of Supply and Services,1996:1-10.
[3] Public Health Agency of Canada.Laboratory biosafety guidelines[M].3rd ed.Ottawa:Minister of Public Works and Government Services,2004:1-12.
[4] Public Health Agency of Canada.Canadian biosafety standards and guidelines[M/OL].[2022-04-01].http://canadianbiosafetystandards.collaboration.gc.ca.
[5] Canadian Food Inspection Agency.Containment standards for veterinary facilities[S].Ottawa:Agriculture and Agri-Food Canada,Minister of Supply and Services Canada,1996:1-30.
[6] Canadian Food Inspection Agency.Containment standards for laboratories,animal facilities and post mortem rooms handling prion disease agents[S].Ottawa:Canadian Food Inspection Agency,2005:1-10.
[7] Public Health Agency of Canada.Canadian biosafety standards (2nd ed)[S/OL].[2022-04-01].http://canadianbiosafetystandards.collaboration.gc.ca.
[8] Public Health Agency of Canada.Canadian biosafety handbook[M].2nd ed.Ottawa:Minister of Health and the Minister of Agriculture and Agri-Food,2016:1-60.
[9] U.S.Center for Disease Control and Prevention.Biosafety in microbiological and biomedical laboratories(6th edition)[M/OL].[2022-04-01].https://www.cdc.gov/labs/BMBL.html.
[10] 中国合格评定国家认可中心，国家质量监督检验检疫总局科技司，中国疾病预防控制中心，等.实验室生物安全通用要求：GB 19489—2008[S].北京：中国标准出版社，2008:7-11,23-24.
[11] 中国建筑科学研究院，江苏双楼建设集团有限公司.生物安全实验室建筑技术规范：GB 50346—2011[S].北京：中国建筑工业出版社，2012:5-9,32.
[12] 加拿大公共卫生署.加拿大生物安全标准与指南[M].赵赤鸿，李晶，刘艳，译.北京：科学出版社，2017:Ⅵ.
[13] 曹冠朋，曹国庆，张彦国，等.国内外生物安全实验室标准体系检测要求对比[J].暖通空调，2022,52(2):16-22.
Development process and enlightenment of Canadian laboratory biosafety handbooks and standards
Abstract: This paper presents the development history of Canadian laboratory biosafety handbooks and standards, studies their revision ideas and development trends, and focuses on the development direction of laboratory biosafety standards in China from four aspects: the necessity of national standards, the complementarity of standard and guidelines, the concept of the same health and the importance of performance verification, so as to provide references for the formulation and revision of biosafety related standards in China.
Keywords: laboratory; biosafety; Canada; standard; handbook; development direction;
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